![]() ![]() "As a group, RSM Finance is proud of the quality of our research, our programmes, and the renowned finance scholars who like to visit, teach and learn with us," says Professor Verbeek. The group also organises highly visible academic conferences each year, including the Professional Asset Management and Erasmus Liquidity series, which feature renowned international keynote speakers. Corporate finance is the area of finance that deals with the sources of funding, and the capital structure of corporations, the actions that managers take. Such speakers as Daron Acemoglu (MIT), Harrison Hong (Princeton), Maureen O’Hara (Cornell), and Lucian Taylor (Wharton School of Business) present each week to an audience that includes faculty and PhD researchers. "The Erasmus Finance Group has an outstanding weekly seminar series that can compete with those from the best business schools in the world," says Professor Verbeek. We co-operate with the industry on topics such as sustainable finance and climate risk, and we share our latest research with each other during our lunchtime Brown Bag Seminars – it's inspiring to work as a community of finance." Weekly seminars Rabobank offers high-end products and advisory solutions to help you finance your assets, improve financing structure, manage working capital and generally. "Our research and education focus on positive change that enables people and organisations to thrive. We are a partner to European credit institutions, supporting them to free up resources for their respective core business by reducing. "We address a wide variety of areas – research into corporate finance, the predictability of stock returns, asset management, sustainable finance, credit risk, financial innovation, FinTech, entrepreneurial finance and corporate governance, among others," says Professor Verbeek. ![]() RSM Finance is part of the Erasmus Finance Group, which includes faculty from the Erasmus School of Economics (ESE) at Erasmus University Rotterdam.
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![]() The current installer available for download occupies 3.6 MB on disk. It is equipped with numerous tools that process, modify files. The program is categorized as Design & Photo Tools. Design & Photo downloads - DrawBerry by Raphael Bost and many more programs are available for instant and free download. The program uses the original SVG standard. The application has a control panel, which contains the latest tools, options. Strawberry Perl for Windows The Perl for MS Windows, free of charge Perl is a programming language suitable for writing simple scripts as well as complex applications see Strawberry Perl is a perl environment for MS Windows containing all you need to run and develop perl applications. The software interacts with gradients, text, shapes, metadata. Powerful graphics editor is equipped with numerous useful features. Buy Kiddylicious Strawberry Wafers 6+ Months online at ASDA Groceries. What looks like sunlight streaming in is, upon closer inspection, artificial light coming through a fake window. You can free download Inkscape official latest version for Windows 10 in English. Ohanaware uses Paddle as their payment processor.The same great prices as in store, delivered to your door or click and collect from. For a limited time, Ohanaware are running a promotion whereby this new version is available for only $39.99 (USD). ![]() HDRtist NX 2.2 offers a FREE no-obligation 30 day trail. HDRtist NX 2.2 is available right now from the Ohanaware web site.
![]() The wattage of a steam generator iron determines the power of the steam output. Look for a model with a high steam output for efficient and effective ironing. Steam output is an important consideration when choosing a steam generator iron. ![]() Consider the size and weight of the iron and choose a model that is comfortable for you to use. Steam generator irons are larger and heavier than traditional irons. Size and weight of the steam generator iron Look for a model with a tank size that is suitable for your ironing needs. A larger tank is ideal for heavy-duty ironing tasks or larger loads, while a smaller tank is suitable for occasional ironing tasks. The water tank size determines how long you can iron before needing to refill the tank. Consider your budget and choose a model that offers the features you need within your price range. However, the cost can vary widely depending on the features and capabilities of the iron. Steam generator irons are typically more expensive than traditional steam irons. Here are the key factors to consider: Cost When buying a steam generator iron, there are several important factors to consider to ensure that you choose the best model for your needs. What to consider when buying a steam generator iron? Soleplate material: Microsteam 400 HD Laser ![]() The iron also has a unique silence technology that reduces noise levels during use. It features a durable soleplate that glides smoothly over fabrics and an anti-scale system to prevent limescale buildup. The Rowenta Silence Steam Pro DG9249 is a powerful and efficient steam generator iron that produces plenty of steam to remove wrinkles from any fabric. ![]() This sounds odd at first, but it actually allows the player to more easily streamline dodging into their attack routines. The game’s dodging mechanic requires pressing both the Square and X buttons on the PlayStation 4 controller simultaneously (Lost Soul Aside will be a timed PS4 exclusive when it's released). Players can attack using a variety of different melee weapons (three were included in the demo) and they can even switch between weapons mid-combo, allowing them to mix things up by utilizing each weapon’s different strengths. ![]() Lost Soul Aside was created by a single developer, an industrial design student named Yang Bing who hails from mainland Asia, and it has already drawn comparisons to AAA games like Devil May Cry, Ninja Gaiden, Bloodborne, and even Final Fantasy 15.ĭuring PSX 2017, a small-scale playable demo for Lost Soul Aside was available, and it proved to be so popular that it drew in incredibly long lines of PSX attendees hoping to get their chance to play it.Īccording to reports from those who did get to play the demo, Lost Soul Aside features a combat system that aims to combine the deliberate pacing of Dark Souls with the more action-packed spectacle of Final Fantasy. If the name Lost Soul Aside sounds familiar that’s because it was actually first unveiled way back in August of 2016. This year’s PlayStation Experience event wasn’t very memorable (at least in comparison to the Game Awards event which happened only a few days earlier), but there was one game present on the PSX showroom floor which ended up being a surprise hit: the action-combat game Lost Soul Aside. ![]() Michelson, Hendrik Lorentz, and Henri Poincare among others, contributed to what would ultimately transform theoretical physics and astronomy, the scientist credited with compiling and describing the theory of relativity and the Lorenz Transformation was Albert Einstein. While many scientists, including Ernst Mach, Albert A. Despite Leibniz's efforts, this Newtonian concept of physics remained prevalent for nearly two centuries. He argued that absolute space was necessary in order to account for cases where a relationalist perspective could not fully explain an object's rotation and acceleration. Since this example showed that the concavity of the water was not based on an interaction between the bucket and the water, Newton claimed that the water was rotating in relation to a third entity, absolute space. If the bucket's rotation is then stopped, the water remains concave during the period it continues to spin. In this argument, water in a bucket hanging stationary from a rope begins with a flat surface, which becomes concave as the water and bucket are made to spin. ![]() One of the prominent arguments that arose from the correspondence between Newton's spokesman Samuel Clarke and Leibniz is referred to as the bucket argument, or Newton's bucket. It is simply the way in which humans subjectively perceive and sequence the objects, events, and experiences accumulated throughout their lifetimes. Within this argument, known as relational time, time itself cannot be measured. According to Leibniz, time is nothing more than a concept similar to space and numbers that allows humans to compare and sequence events. ![]() Newton's realist view is sometimes referred to as Newtonian time.Ĭontrary to Newton's assertions, Leibniz believed that time only makes sense in the presence of objects with which it can interact. Relative time on the other hand, is what humans actually perceive and is a measurement of "duration" through the motion of objects, such as the sun and the moon. He argued that absolute time exists and flows without any regard to external factors, and called this "duration." According to Newton, absolute time can only be understood mathematically, since it is imperceptible. In Newton's Philosophiæ Naturalis Principia Mathematica, Newton tackled the concepts of space and time as absolutes. Aristotle's view is solely one amongst many in the discussion of time, the most controversial of which began with Sir Isaac Newton, and Gottfried Leibniz. Interestingly, he was also one of the first people, if not the first person, to frame the idea that time existing of two different kinds of non-existence makes time existing at all, questionable. He also believed that time was infinite and continuous, and that the universe always did, and always will exist. One of the earlier views was presented by the ancient Greek philosopher Aristotle (384-322 BC), who defined time as "a number of movement in respect of the before and after." Essentially, Aristotle's view of time defined it as a measurement of change requiring the existence of some kind of motion or change. There exist various concepts of time that have been postulated by different philosophers and scientists over an extensive period of human history. Oct., Dec.-31 daysįeb.-28 days for a common year and 29 days for a leap yearĢ4 hours or 1,440 minutes or 86,400 seconds The following table shows some common units of time. However, due to how time is defined, there exist differences in how calculations must be computed when compared to decimal numbers. Like other numbers, time can be added or subtracted. ![]() ![]() I converted to MacJournal (importing my Daily Journal entries in RTF) in about 2001 while it was still free, but exported everything out to Journler in RTF after MacJournal sold out because I could see it heading for the expensive bloatware it's become. I converted to Journler after starting a journal in Daily Journal for Windows on May 5, 1994, and have made entries just about daily ever since. I have encountered no difficulties, and there are multiple export opportunities in Journler (many outputs in many formats). I'm using OSX 10.6.8 now after using 10.6.7 and all versions back to early 2006 when I converted to Journler. To update some of the comments below, I thought I should make some new ones. I´m so glad I managed to get the Journler working again! My problem appeared to be a bad file name inside Entry 64 - Resources - a picture file name with two periods. If it still crashes within minutes – jump to A and remove more Entries in the Journler Entries folder until you have caught the troublesome. It should ask you to locate the new Journler test folder due to the name change. Trash some or half of the Entry folders there. (Mine was in the hidden directory ~Library.) I moved the Journler folder to the personal "Document" folder. 6.Journler 2.6b4 crashes solved after upgrade from 10.6.8 – works with Mac OS X, 10.10.5 now!Īfter crashing more or less instantly after a Mac system upgrade I finally solved the problem by doing this: To ensure the complete removal, it would be better to unhide the Library folder permanently. In the upper-left corner of the screen, hold the “Option” key on your keyboard, click “Go” on the Finder, and select “Library” to open the Library folder. Otherwise, just do the following to clean them out. Usually they are very small, so if you attempt to reinstall the application, you can keep them. So this is teaching you how to delete the Support and Preference Files from it, which are those left behind after you remove Chronories 1.1.1 application. In the entire removal process, the Library folder could be a blind spot to many users. This will permanently remove Chronories 1.1.1 and everything inside, freeing up the hard drive space on your Mac. It will ask for your confirmation, also click “Empty Trash” on the message. Right-click on the Trash icon, select “Empty Trash”. In the list of installed applications, select Chronories 1.1.1 as a target, and hit “Run Analysis”.ĭo it once you are certain that you will never use Chronories 1.1.1 again (or in a short time at least). Download - Install - Run App Uninstaller 2. What I’m only interested in is how to quickly get things done”. In the very beginning, I would like to introduce an easy approach to uninstall this app on Mac, just in case you are like “Geez, don’t put me through the knowledge. Using App Uninstaller by to Breezily Remove Chronories 1.1.1 I believe after going through the whole process, you will be much more familiar with your Mac. The following are specific steps for you to fully remove Chronories 1.1.1. Regards to removals on macOS, keywords shall be Finder, Library, Preference, and Application Support instead. Let’s temporarily isolate other Windows logicality from our mind, forget about the Start menu, Control Panel, Registry Editor, etc. If you don’t deal with them termly, issues would be generated. ![]() So there is one thing you can be sure of: too many junks will slow down your computer, and they are accumulating during the operation. Removing the useless applications from your computer is still one of the simplest ways to speed up your system, where everything lives to work, occupying part of the hardware resources including hard drive space and memory. Now go with how to correctly remove Chronories 1.1.1. If you happen to be a newbie of Mac Computer, take the chance to learn something. ![]() This page can help you understand the basic knowledge of system maintenance, guiding you through the confusion of removal problems. Removals on macOS are quite different from those on Microsoft Windows OS. ![]() ![]() ![]() Whether you’re looking to relax, challenge yourself, or play with friends, Poki games are an excellent choice. Overall, Games provide a fun and engaging way to spend your free time, and the ability to save your progress through a registered account adds a convenient touch. The games range from arcade to shooting and battle to team mode. If you want to pass your time in a fun and entertaining way then poki online games are for you. Poki games are the best entertainment for everyone who is getting bored. The Legendary Trials: Craig Of The Creek.Fire Boy and Water Girl: 1 Forest Temple.Some of the top online poki games which are sure to be enjoyed by everyone are as follows: Next time you want to continue playing, log in to your account, find the game, and click on the “Load progress” button.Play the game, and when you are ready to stop, click on the “Save progress” button.After a year, they decided to come back to the beach. But before they left from the beach, they had buried the treasure somewhere on beach. ![]() Before you start playing, make sure you see the “Save progress” option somewhere on the game screen. On previous chapter of Raft wars, little brother Simon had found a treasure on beach and Simon and his brother defended that treasure against to pirates.Find the poki game you want to play and click play on it.Fill in the required information to create an account and log in to it.If you want to save your progress in poike games then you need to follow the given instructions: If you have further questions you can go through the FAQs.Select the game and click on the play button.Browse through the categories you are interested in. Mouse - Click and draw to shoot Can I play multiplayer such raft wars 2 game unblocked, Cool play Raft Wars 2.Go to the games online poki website through your desktop, tabs, or phones.Following are the instructions on playing games on poki: Unblocked games for girls and boys consist of various genres that are up to date and the latest. To play poki games free fire you need to follow some instructions. Theres only one rule: the last man standing wins. Press your button to bounce upwards and stay in the raft. Raft Wars is a fun shooting game online, similar to the famous PC game Worms, and you can play it online at Cool Games. It's where I take games I played from my childhood that I'd usually play on. Get in the raft and try to avoid all kinds of obstacles on your way. This is the first episode of my new series Cool Math Gameplays. So just buckle up and get ready to have unlimited fun. Tube Jumpers is a free 2 player battle game, where you have to stay in the moving raft as long as possible. Designed in a way that everyone can make spirits and adventure. The pokie games unblocked are user friendly and venture. These games are available online for your desktop as well as your smartphone. Poki games consist of different catalogs that are free. Whether you are a youngster or an adult, games poki have got everything under control. Join the fun today! What Are Poki Games Online? Expect the highs of victory and the lows of defeat, it’s all part of the game. Whether you’re playing solo or battling it out with friends, Poki offers the perfect gaming experience. Cool Math Games Run 3 unblocked is a popular game among the kids We share. If they are well forged, the warriors will be able to endure longer in battles. They are also the creators of Raft Wars 2 and Raft Wars Multiplayer.Get ready to level up your gaming experience with Poki Games. Raft Wars at Cool Math Games: After finding hidden treasure buried on the. Raft Wars Mechanical Commando Hellvolution Bad Ice-Cream Hambo Droid Assault Bad Ice-Cream 2 How to play Jacksmith Prove that you are the best smith in this kingdom and provide the army with the best weapons ever. Raft Wars is created by Martijn Kunst and TinyDobbins, based in the Netherlands. Yes, the Raft Wars Multiplayer of Raft Wars is created with multiplayer mode where you play against online players. Mouse - Click and draw to shoot Can I play multiplayer? Originally built in Flash, you can now enjoy Raft Wars in HTML5 on your desktop or mobile device. Raft Wars is a fun, level-based shooting game created by Martijn Kunst, where you and your brother Simon will need to defend your treasure from enemies of all kinds! Initially armed with your raft and only some tennis balls, you'll need to focus on your aim and power in order to defeat vikings, pirates, gangs, and more! Hit your opponent to knock them off their raft or wear down their health until they fall in! Earn coins by making strategic shots in order to unlock grenades, rockets, and raft upgrades. One of the most impactful pieces of information I have received from others who are in remission is, TIME. I would like to say I have come through the worst of it, but there are still setbacks from time to time. I had to learn how to do everything all over again. ![]() I had a G-Tube in my stomach so I could receive nutrients and I was completely dependent on my Port for all other hydration and meds. The worst of my days involved loosing the ability to walk, talk, swallow and more. ![]() My motto was, "Whatever it takes, I will do Whatever it Takes". I was quickly put on PICC lines and ports, I have been on IV therapy for 3 years now, along with every Oral med, supplement, experimental therapy and much much more. Chronic Lyme Disease would now be what I was facing. And not just Lyme disease from a tick bite 3 days ago on a camping trip, it was Lyme disease from 20 years ago, in our yard playing as a little girl. Long story short I found out that missing puzzle piece was Lyme Disease. But it was like I kept hitting a wall right before the finish line. I went through many different types of medicine (Western, Natural, Holistic, Alternative) and each part of that journey brought me one step closer to being healthy and back to the living. I took matters into my own hands and started researching, hours upon hours upon hours. I could not live in a state of desperation and deterioration. I tell most people I googled my way back to health. But still there were no answers, just support. I was one of the lucky ones that had doctors who believed I was truly sick and never made me feel crazy. I was aware enough to easily figure out that whatever was going on was not normal, nor easy for the doctors to figure out. The symptoms piled on as the days, months and years passed. My early childhood is when my tiny body, that should have been growing big and strong, started to wither. But waiting in the wings of life was a disease I knew nothing about. ![]() I was immensely blessed to be born into the most loving, supportive and unconditional family. Such a long story, a long journey I have traveled. What's your favorite meal of the day? Chow down on breakfast, lunch, and dinner at Porthole Restaurant and taste test your way through the menu. Want top-notch taste for less than top-dollar prices? Porthole Restaurant s mid-range cuisine is sure to satisfy on both fronts, where pennies stretch into perfectly seasoned platters. ![]() You'll also find plenty of safe spaces to lock up your bike if you prefer to cycle to the restaurant. Porthole Restaurant prides itself in its delicious catering.īoth street parking and lot parking are available near Porthole Restaurant. Free wifi is on hand here as well.Įating on the go? Order some tasty take out from this restaurant. The Largest Waterfront Deck right in the heart of Portlands Old Port. Sit outside when the weather is fine - Porthole Restaurant has a lovely patio to enjoy a warm day. Round up your coworkers and head to Porthole Restaurant for happy hour. Load up the mini-van and bring the kids to this restaurant - they'll love the menu and scene here as much as mom and dad. Check out the daily entertainment on the deck at ‘SOLD OUT’ CONCERT CRUISES ARE SOLD OUT No other tickets will be available. This restaurant's fully stocked bar is a perk for patrons who enjoy a fine wine (or more) with their meal. The Porthole Restaurant, our affiliate, is located on Custom House Wharf for dining prior or after cruise. Our wines are priced to be enjoyed.Your taste buds are calling for some down home American cooking from Porthole Restaurant. Our spirit collection includes an interesting selection of Maine made options. We make seasonal rotations and feature Rising Tide, Maine Beer Company, Fore River Brewing, Geary’s, Shipyard, Foundation, Bunker, Allagash and many others. Our tap is dedicated to helping our guests discover some of the best beers Maine has to offer. One of the owners is a vegetarian who is constantly learning new ways to prepare food for gluten free diets and the ever growing population suffering from various food allergies. ![]() We’re told we have the finest Reuben, Steak’n’Cheese,Fish Sandwich, Macaroni and Cheese, and Clam Chowder in town. Our white fish, clams, mussels, scallops and lobster are harvested near-by and often by fishermen who are our customers and friends. This means we are committed to supporting sustainable seafood practices and always having Gulf of Maine seafood on our menu. Live acoustic style music every evening, local beers, and the freshest most sustainable seafood choices that Portland has to offer make Andy’s Old Port Pub a perfect gathering place.Īndy’s is proud to be one of a select group of eateries who have chosen to partner with The Gulf of Maine Research Institute’s (GMRI) Culinary Partners Program. Very entertaining and stylish place to hang out.The Porthole Restaurant is featured on the The Maine Event Scavenger Hunt. Our bartenders and cooks do everything they can to accommodate special orders. Special dietary needs? Feel free to ask for something off the menu. ![]() ![]() One of the owners is vegetarian so there are always meat free options to choose from. The occasional tourist – fortunate enough to find their way to us – always gets a warm welcome and an authentic taste of Portland’s Old Port neighborhood.Īndy’s menu includes the freshest of fish & chips one of the best burgers in town home made meatloaf and macaroni and cheese salads and wraps and pizzas that rival New York’s finest. Our main entry is five steps above street level and not visible from the sidewalk. Nestled in between Gilbert’s Chowder House and the Casco Variety Store, we can be a tricky little Pub to find. Serving Outstanding Pub Fare from 11AM – 10:30PM DailyĪndy’s Old Port Pub is a waterfront watering hole frequented by locals, islanders, fishermen, music lovers, and more. ![]() “If we are proven correct, an effective staph vaccine may not be too far away.”Ĭo-authors include: J.R. ![]() “It is even possible that the same principle might also explain why many other hard-to-make vaccines have failed,” he said. In combination with other experiments, Liu said the findings suggest that faulty memory of a pathogen and its corresponding immune response are likely explanations for the failed staph vaccine trials in humans. “We surmised that if we could vaccinate only against the protective component of IsdB, we might be able to prevent suppression by bad immune response memory,” said Tsai.Īnd, in fact, that is what the scientists found: When they vaccinated mice solely against the protective component of the IsdB protein, the animals were effectively protected, even if previously exposed to S. When researchers tried mixing human IsdB antibodies with protective antibodies made from the vaccine, the latter stopped working. Subsequent boosters primarily amplified the ineffective antibody response and, compounding the problem, the ineffective antibodies competed with any existing, protective antibodies. But in mice previously exposed to staph, the vaccine generated only antibodies against the unprotected portion of the IsdB protein, leaving bacterial functioning unimpaired. In mice unexposed to normal staph, the IsdB vaccine worked, generating antibodies that targeted the whole protein and disrupted bacterial functions. aureus to acquire needed iron for functioning. To test their hypothesis, Liu, Tsai and co-authors conducted a series of experiments simulating one of the largest failed staph vaccine trials in humans, which targeted the IsdB protein used by S. “If mice had staph infections before vaccination, we think that the vaccine candidates might not work.” aureus, but humans are exposed to staph beginning in the first weeks of life and, in order to coexist, staph appears to have developed many strategies to render ineffective our immune response against them,” Tsai said. “Staph vaccines appear so easy to make in laboratory mice because they rarely see S. aureus has evolved defenses to fend off therapeutic attack. aureus respond well to potential vaccines because they are entirely new, human versions do not work because S. With first author Chih-Ming Tsai, PhD, a project scientist in his lab, and others, Liu hypothesized that while laboratory mice with no previous exposure to S. Within two months, half of babies host active colonies and abundant antibodies to fend off most infections. Humans, by contrast, are very quickly exposed to S. Laboratory mice used in research are engineered (bred/raised/maintained) to be free of the specific target pathogen they have had little or no exposure to S. aureus, including the mechanism that explains why vaccine trials have so far failed and ways to overcome that.įundamentally, the difference lies in prior exposure to the pathogen, the authors write. In a new paper, publishing Jin the journal Cell Host & Microbe, senior author Liu and colleagues say they may have found the answer to the conundrum of S. “Vaccines are the most effective way to cut down that health burden and reduce antibiotic resistance,” said Liu, pointing to successes with childhood inoculations and the more recent COVID-19 vaccines. A study published in 2022 estimated that bacterial antimicrobial resistance resulted tens of millions of infections and 1.2 million deaths worldwide in 2019, with MRSA as the primary driver. MRSA is the primary source of infections acquired within hospitals and other health care settings, such as nursing homes. aureus (MRSA), a type of staph bacteria that has become increasingly resistant to antibiotics commonly used to treat ordinary staph infections. The question has gained greater urgency with the spread of methicillin-resistant S. ![]() “None of these human trials have worked and scientists have struggled to find a reason.” “It’s a longstanding and one of the most enigmatic issues of the staphylococcal field,” said George Liu, MD, PhD, professor of pediatrics at University of California San Diego School of Medicine and chief of the Division of Infectious Diseases at Rady Children’s Hospital-San Diego. In all of the subsequent human trials, however, these vaccine candidates failed. Occasionally, though, it can become an opportunistic pathogen, causing skin and bloodstream infections or food poisoning.įor more than a century, scientists have searched for an effective vaccine, including at least 15 successful preclinical studies using animal models in the past 30 years. Newswise - For the most part, the bacterium Staphylococcus aureus is common and harmless, posing no threat to humans with whom they coexist. |